Nuclear Calcium Transients

Nuclear calcium transients: Hermes Propylaios in the heart.

O cunning guide, son of Maia, I fear that you might steal my lyre and my curved bow. For you hold the office from Zeus to establish deeds of exchange among men throughout the fertile earth. But if you would suffer to swear the great oath of the gods for me, either by nodding your head or by the mighty water of the Styx, you would accomplish everything pleasing to my own heart. —Homeric Hymnes 1...

Nuclear Calcium Transients : Hermes Propylaios in the Heart Running title

Mechanism of intracellular calcium transients.

Calcium ions mediate extracellular signals on intracellular processes. The signalling system based on transient rises or oscillations of the cytoplasmic calcium concentration has potential advantages. The relevant mechanisms of intracellular concentration changes include calcium-induced calcium release and calcium dependent inactivation of calcium release. A model has been devised based on thes...

Measurement of calcium transients and slow calcium current in myotubes

The purpose of this study was to characterize excitation-contraction (e-c) coupling in myotubes for comparison with e-c coupling of adult skeletal muscle. The whole cell configuration of the patch clamp technique was used in conjunction with the calcium indicator dye Fluo-3 to study the calcium transients and slow calcium currents elicited by voltage clamp pulses in cultured myotubes obtained f...

Repetitive calcium transients in hormone-stimulated cells.

Many hormones that act via the phosphoinositol .cycle induce transient rises in cytoplasmic free Ca2+ in a variety of cell types (Berridge et al., 1988). To this list may now be added vascular smooth muscle cells from rat and rabbit aorta in primary culture; both angiotensin I 1 and ATP induce repetitive free Ca2+ transients in spread single cells microinjected with aequorin (Fig. 1). The mecha...